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VIP (10mg)

Table of Contents

  • Quickstart Highlights

VIP (10mg) protocols focus on Vasoactive Intestinal Peptide, a naturally occurring neuropeptide involved in regulating immune response, inflammation, vascular tone, and smooth muscle activity. It is being studied for its potential role in supporting respiratory function, neurological balance, gut health, and inflammatory regulation. This guide outlines a subcutaneous administration approach optimized for the 10 mg vial format.

  • Reconstitute: Add 2.0 mL bacteriostatic water → 5 mg/mL concentration
  • Typical daily range: 100–300 mcg once or twice daily (subcutaneous)
  • Easy measuring: At 5 mg/mL, 1 unit = 0.01 mL = 50 mcg (0.05 mg) on a U-100 insulin syringe
  • Storage: Lyophilized: store at −20 °C; after reconstitution, refrigerate at 2–8 °C and use within 2–4 weeks
  • Protocol Overview

Concise summary of the subcutaneous regimen.

  • Goal: Support immune modulation, inflammation balance, and neuro-respiratory function
  • Schedule: Daily subcutaneous injections, often split into 1–2 doses
  • Dose Range: 100–300 mcg per day
  • Dosing Protocol

Suggested approach for the 10 mg vial format.

  • Start: 100 mcg once daily to assess tolerance
  • Target: 200–300 mcg per day
  • Frequency: Once or twice daily (subcutaneous)
  • Vial Duration: One 10 mg vial lasts approximately 30–100 days, depending on dose
  • Timing: Morning and/or evening; consistent daily timing preferred
  • Mechanism of Action

Vasoactive Intestinal Peptide (VIP) is an endogenous neuropeptide that functions as both a neurotransmitter and immunomodulator. It binds to VPAC receptors (VPAC1 and VPAC2), which are widely expressed in immune cells, the central nervous system, and smooth muscle tissues.

Through these receptors, VIP may help regulate inflammatory cytokine production, support vasodilation, and influence autonomic nervous system balance. It also plays a role in mucosal barrier integrity in the gut and respiratory tract. Research suggests VIP may help shift immune activity toward a more regulated, anti-inflammatory profile while supporting tissue protection mechanisms.

  • Potential Benefits & Side Effects

Observations based on preclinical and early clinical research.

Potential Benefits:

  • May support immune system balance and inflammation regulation
  • May assist respiratory function and airway relaxation
  • May support gut barrier integrity and digestive health
  • May have neuroprotective and calming effects on the nervous system

Possible Side Effects:

  • Facial flushing or warmth due to vasodilation
  • Mild headache or lightheadedness
  • Temporary drop in blood pressure in sensitive individuals
  • Injection-site irritation
  • Long-term safety and dosing in humans are still under investigation