GHK-CU (100mg)

GHK-Cu (100mg) protocols focus on this naturally occurring copper peptide complex (glycyl-L-histidyl-L-lysine bound to copper), widely studied for its role in skin regeneration, wound healing, hair growth, and anti-aging support. GHK-Cu may help stimulate collagen production, improve tissue remodeling, and support overall cellular repair. This guide outlines a subcutaneous or topical-compatible preparation for the 100 mg vial format.

  • Reconstitute: Add 10.0 mL bacteriostatic water → 10 mg/mL concentration
  • Typical range: 1–2 mg daily (subcutaneous) or topical application as directed
  • Easy measuring: At 10 mg/mL, 1 unit = 0.01 mL = 100 mcg (0.1 mg) on a U-100 insulin syringe
  • Storage: Lyophilized: store at −20 °C; after reconstitution, refrigerate at 2–8 °C and use within 2–4 weeks

Concise summary of the usage approach.

  • Goal: Support skin repair, collagen synthesis, and hair regeneration
  • Schedule: Daily use (subcutaneous or topical, depending on application)
  • Dose Range: 1–2 mg per day (injectable equivalent)

Suggested approach for the 100 mg vial format.

  • Start: 1 mg once daily to assess tolerance
  • Target: 1–2 mg daily
  • Frequency: Once per day (subcutaneous) or divided topical use
  • Vial Duration: One 100 mg vial lasts approximately 50–100 days depending on usage
  • Timing: Flexible; often applied/injected in the evening for recovery support

GHK-Cu is a naturally occurring tripeptide that binds copper ions and plays a key role in tissue repair and regeneration. It has been shown to activate genes involved in wound healing, collagen synthesis, and antioxidant defense.

GHK-Cu may stimulate fibroblast activity, increase production of collagen and glycosaminoglycans, and promote angiogenesis (formation of new blood vessels). It also exhibits anti-inflammatory and antioxidant properties, helping to improve skin elasticity, reduce wrinkles, and support hair follicle health. Additionally, it may assist in remodeling damaged tissue and improving overall skin quality.

Observations based on preclinical and cosmetic research.

Potential Benefits:

  • May improve skin elasticity and reduce fine lines
  • May stimulate collagen production and skin regeneration
  • May support hair growth and follicle health
  • May enhance wound healing and tissue repair

Possible Side Effects:

  • Generally well tolerated
  • Mild skin irritation or redness (topical use)
  • Injection-site irritation (if injectable)
  • Long-term systemic safety data remain limited; use remains investigational