GHK-CU (50mg)

GHK-Cu (50mg) protocols focus on this naturally occurring copper peptide (glycyl-L-histidyl-L-lysine bound to copper), studied for its potential to support skin regeneration, wound healing, hair growth, and anti-inflammatory activity. GHK-Cu may stimulate collagen production and tissue remodeling while promoting overall cellular repair. This guide outlines a subcutaneous or topical use approach optimized for the 50 mg vial format.

  • Reconstitute: Add 5.0 mL bacteriostatic water → 10 mg/mL concentration
  • Typical daily range: 1–2 mg (subcutaneous) or topical application as needed
  • Easy measuring: At 10 mg/mL, 1 unit = 0.01 mL = 100 mcg (0.1 mg) on a U-100 insulin syringe
  • Storage: Lyophilized: store at −20 °C; after reconstitution, refrigerate at 2–8 °C and use within 2–4 weeks

Concise summary of the regimen.

  • Goal: Support skin repair, collagen synthesis, and hair health
  • Schedule: Daily subcutaneous injections or topical application
  • Dose Range: 1–2 mg per day (injectable) or variable topical use depending on formulation

Suggested approach for the 50 mg vial format.

  • Start: 1 mg once daily to assess tolerance
  • Target: 1–2 mg daily
  • Frequency: Once per day (subcutaneous) or applied topically 1–2 times daily
  • Vial Duration: One 50 mg vial lasts approximately 25–50 days, depending on dosing
  • Timing: Flexible; consistent daily use recommended for best results

GHK-Cu is a copper-binding peptide naturally present in human plasma, saliva, and urine. It plays a key role in tissue repair and regeneration by activating genes involved in collagen production, antioxidant defense, and wound healing.

It may stimulate fibroblast activity, increase glycosaminoglycan synthesis, and promote angiogenesis. GHK-Cu is also known to modulate inflammation and support hair follicle function, which contributes to its potential role in skin rejuvenation and hair regrowth. Its gene-regulating properties have been widely studied in regenerative medicine research.

Observations based on preclinical and early-stage research.

Potential Benefits:

  • May improve skin elasticity and reduce wrinkles
  • May stimulate collagen production and tissue repair
  • May support hair growth and scalp health
  • Anti-inflammatory and antioxidant properties

Possible Side Effects:

  • Generally well tolerated
  • Mild skin irritation (topical) or injection-site reactions
  • Rare sensitivity to copper peptides in some individuals
  • Long-term safety data for high-dose use remains limited; investigational use only